If a work request is created from the asset object by right-clicking on it (this can be done from the My Desk view, Assets tab on either the HIerarchy or Listing sub-tab), when it is uploaded the title will not be on the new Work Request. Since this is a required element, the Work Request can become unuseable.
This will be corrected in an upcoming release. Until then, please tell users to create work requests from the My Desk view, Work tab, Work Requests sub-tab. Alternatively, if you are using remote security profiles, you can make the New Work Request method unavailable for the Asset class on all Profiles.