If you created a Server Manager instance while running APM Configuration as an administrator, you might later encounter an error when trying to save settings. You can try either of the following.

• Close APM Configuration and run it as an administrator
• Add your user to the list of users allowed to edit the settings file. Navigate to
  C:\ProgramData\Bentley\IvaraEXP\Settings\default\7.21\broker.xml
  Right-click broker.xml and click Properties. In the Properties dialog, select the Security tab.