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If you do a default installation of Seq, it will live on the C drive of that server.
Seq is a hungry creature and will use up 90% of the RAM and all the available disk space.
To control Seq's memory usage...
Note that Seq has its own log files, though they are probably not growing as fast as the extent files. Those can also be configured to go to a different drive. Refer to the “reinstall” link in step 3 for details.