Temperature Frequency Simulator

I've been trying to run a temperature frequency simulation for an 8 room building.

ive set everything up (repeatedly) and left the simulation to run for several hours / overnight several times.

The simulation makes never seems to finish. the calculation needs to be completed and sent out ASAP

What reasons can there be for a simulation getting stuck and providing no error codes and what can I do to make it work? 

Kind Regards

David