How to resolve Exception has been thrown by the target of an invocation.

When I was trying to open wiring manager following error message pop-up

Then I followed steps to resolve the above error,

1) So I open and checked the following status.

2) I also tried following to avoid the above error. 

  1. Close Promis.e or Bentley Substation.
  2. Rename or delete the following folder:
    Application Data (per-user configuration) - Promis.e

Another error, when trying to insert the symbol, following error message pop-up

Then restart the system, PC, SQL server. But still, error not resolved. 

Please help to resolve.