Graph from comma delimited list

Is there an easy way to produce a line on a plot from a comma delimited list of coordinates?

Specificaly:

Independent variable = <<expressionX1>>,<<expressionX2>>,<<expressionX3>>,<<expressionX4>> ...

Dependendant variable = <<expressionY1>>,<<expressionY2>>,<<expressionY3>>,<<expressionY4>> ....

to produce a line with coordinates (X1,Y1) , (X2,Y2) , (X3,Y3) , (X4,Y4) ...

Plot would have keyset PointID, Depth to produce a plot for each sample.

Not sure if this is possible but before I get into more complex things like scripts or data structure conversion I want to make sure there is not a simple way I am overlooking.

Thanks