We have seen these problems:
Prior to gINT V8i 08.3.x, gINT user files (project .GPJ's, library .GLB's, data template .GDT's, etc.) were installed with the gINT program files under C:\Program Files or C:\Program Files(x86). In Windows Vista and Windows 7, these locations often have restrictions to prevent users from changing any files stored there. This can cause the above behavior. Please Move any gINT files out of the Program Files Directory.
Any gINT files you will be editing need to be moved to a different location, one where you know you have full control. My Documents is often a good location if it is backed up regularly. If not, then perhaps a network drive is best. Sometimes it can be tricky to find all the files, as Windows will often move or copy the files to a different hidden location. If this is the case, it will appear to gINT as if the files are in C:\Program Files when they are actually in this hidden location. To find this hidden location do an Internet search for "find virtual store" and either "Windows 7" or "Vista", appropriate.